Sheep'S Milk Cheese Histamine Information

Sheep's milk cheese, like other dairy products, has the potential to influence histamine levels in the body due to its composition and ageing process. The effect on histamine levels largely depends on the fermentation and ripening period of the cheese. Long-ripened cheeses, particularly hard cheese, are known to have a higher histamine content due to the activity of microbial decarboxylase enzymes over time. This enzyme promotes the conversion of histidine, an amino acid found in such products, to histamine. However, specific information on histamine levels in sheep's milk cheese is scarce and more detailed investigation is required. Certain cheeses can also act as histamine liberators, prompting the body to release histamine. Again, explicit data on sheep's milk cheese as a histamine liberator is insufficient. Many factors, such as the type of cheese, the ageing process, and the individual's tolerance, will determine whether it acts as a histamine liberator or not. Although our knowledge in this area is limited, it's noteworthy that certain diary elements may assist in reducing histamine levels. Casein, a protein found in sheep's milk cheese has been suggested to have a protective anti-histamine effect, possibly related to its role in enhancing the enzymatic activity of diamine oxidase (DAO), the main enzyme responsible for histamine degradation in the body. In conclusion, sheep's milk cheese has the potential to both raise and lower histamine levels, depending on the variety and ageing process of the cheese as well as individual metabolic differences. With the lack of specific research data on histamine and sheep's milk cheese, it's recommended that those with histamine intolerance should take a cautious approach and seek advice from a healthcare professional. It's crucial to understand that these suggestions are based on the existing limited knowledge about the impacts of different types of cheese on histamine levels and much is still to be uncovered. References: - Vlieg-Boerstra BJ, van der Heide S, Oude Elberink JN, Kluin-Nelemans JC, Dubois AE. Mastocytosis and adverse reactions to biogenic amines and histamine-releasing foods: what is the evidence? Neth J Med. 2005;63(7):244–249. - Kuefner MA, Schwelberger HG, Weidenhiller M, Hahn EG, Raithel M. Both catabolic pathways of histamine via histamine-N-methyltransferase and diamine oxidase are diminished in the colonic mucosa of patients with food allergy. Inflamm Res. 2004;53 Suppl 1:S31-2. -Bischoff SC, Mayer J, Wedemeyer J, et al. Colonoscopic allergen provocation (COLAP): a new diagnostic approach for gastrointestinal food allergy. Allergy. 1997;52(5):526–534.