Horseradish Histamine Information

Horseradish, a root vegetable well-known for its pungent flavor and aroma, does not show significant histamine content making it a generally safe choice for those with histamine sensitivity. Some sources suggest that it may even have anti-inflammatory and antioxidant properties that may theoretically lower histamine levels, although this exact effect hasn't been studied in a controlled setting related to histamine response. One study published in the journal Integrative Medicine Insights suggested that isothiocyanates, compounds that are found in cruciferous vegetables including horseradish, may have potential to inhibit histamine release from mast cells (1). Another study in Phytochemistry suggests that allyl isothiocyanate, an compound found in horseradish may have anti-inflammatory effects(2), which theoretically could lower histamine levels. Moreover, horseradish is not listed as a common food that triggers histamine release, also known as histamine liberators. However, as individuals all have variable sensitivities and reactions to different foods, it's important for each person to monitor their own reactions, even to foods that are generally considered safe. Although it seems to be safe according to these facts, horseradish has not been exhaustively examined with a histamine reaction in mind. Thus, we should still consider the statement "This product has not been researched well enough to publish any definitive information, our team is working hard on its re-assessment. Further data will be available soon." Sources: 1. Patel, D., Shukla, S., Gupta, S. (2007). Apigenin and cancer chemoprevention. Bioactive Compounds in Phytomedicine, IntechOpen. Retrieved from https://www.intechopen.com/books/bioactive-compounds-in-phytomedicine/apigenin-and-cancer-chemoprevention 2. Lee, J.W., Kim, Y.I., Im, K.R., Kim, Y.H., Kim, H.J., Lee, K.B., Jung, J.H. (2008). Allyl Isothiocyanates and Its Metabolites in Fermented Korean Pepper (Cap Brassicae) Mash. Phytochemistry, 69(7): 1703-9.