Ginger Beer Histamine Information

Ginger beer is a carbonated, non-alcoholic beverage that is produced through the natural fermentation of prepared ginger, yeast, and sugar. Its peel contains certain bioactive compounds, such as [6]-gingerol, [8]-gingerol, and [10]-gingerol that possess powerful anti-inflammatory and antioxidant effects. Ginger, including ginger beer, appears to have an inhibitory effect on histamine release. These potent compounds inhibit the production and release of histamine from mast cells in the body, preventing an allergic response (1). One study shows that the consumption of ginger inhibits the induction of several genes involved in the inflammatory response. These include genes encoding cytokines, chemokines, and the inducible enzyme cyclooxygenase-2 (2). It is also important to consider the histamine content and histamine-releasing potential of any additional ingredients present in the ginger beer, such as added flavors or sweeteners. For example, if a ginger beer contains pineapple flavor or similar additives, it may indirectly contribute to histamine release because pineapple is known to delay the breakdown of histamine (3). However, it is crucial to remember that each person's body response to histamine is unique, and what triggers a reaction in one person might not cause the same reaction in another. While ginger beer can potentially inhibit histamine production due to the inhibitory effects of ginger, the individual response will always vary based on different factors like genetic predisposition and gut health. 1. S. H. Lee, S. H. Lee, M. S. Son, Y. H. Lee, M. H. Park, S. Y. Chang, E. O. Park, S. O. Lee, Y. S. Park, S. S. Moon, S. H. Lee, S. D. Kim & S. H. Kim (2008): Inhibitory Effects of Gingerol on the Production of NO and Pro-inflammatory Cytokines in LPS-stimulated RAW 264.7 Cells via NF-κB and AP-1 Pathways, International Journal of Pharmacology, 4: 4, 301-307. 2. Lee TY, Lee KC, Chen SY, Chang HH. [6]-Gingerol inhibits metastasis of MDA-MB-231 human breast cancer cells. J Nutr Biochem. 2008. 3. Maintz L, Novak N. Histamine and histamine intolerance. Am J Clin Nutr. 2007.