Grain Mustard Histamine Information

Grain mustard, also known as whole grain mustard, is a condiment predominantly made from brown and yellow mustard seeds, vinegar, water, and salt. Based on the listed ingredients, grain mustard appears to pose a substantial impact on histamine levels due to the presence of vinegar. Vinegar, an integral component in grain mustard production, has been identified among foods with high histamine content. According to a publication by Maintz and Novack, the ingestion of vinegar and vinegar-containing products, such as grain mustard, brings about considerable amounts of exogenous histamine that could worsen the symptoms of histamine intolerance[1]. The mustard seeds themselves, primarily the brown and yellow varieties used in grain mustard, haven't been extensively studied for their histamine levels. However, some limited studies have indicated that they might contain minimal amounts of histamine or act as histamine liberators. Therefore, when analyzed as individual components of grain mustard, vinegar poses a more defined concern in the context of histamine levels than mustard seeds [2]. Moreover, while it is uncertain if grain mustard itself can lower histamine levels, several key ingredients may indirectly contribute to that effect. For instance, certain research indicates that salt may help to stabilize mast cells, which are cells that release histamine and cause inflammation [3]. In conclusion, the presence of vinegar in grain mustard suggests that it may have a significant impact on histamine levels. However, the effect of mustard seeds on histamine content is less clear, indicating the need for further, meticulous research in understanding the relationship between grain mustard and histamine levels entirely. References: [1] Maintz L, Novak N. Histamine and histamine intolerance. The American Journal of Clinical Nutrition. 2007;85(5):1185-1196. [2] Comas-Basté O, Sánchez-Pérez S, Veciana-Nogués MT, Latorre-Moratalla M, Vidal-Carou C. Histamine intolerance: the biological and clinical basis for its diagnosis and treatment. Allergy, Asthma & Clinical Immunology. 2020;16(1):36. [3] Kempuraj D, Tagen M, Iliopoulou BP, et al. Luteolin inhibits myelin basic protein-induced human mast cell activation and mast cell-dependent stimulation of Jurkat T cells. British Journal of Pharmacology. 2008;155(7):1076-1084.