Caramel Sauce Histamine Information

Caramel sauce, a commonly used dessert topping, affects histamine levels due to the ingredients involved in its creation. The primary ingredients in caramel sauce typically include sugar, butter, cream, water, and sometimes vanilla extract. Starting with sugar, its impact on histamine levels is a subject of ongoing research. However, it has been highlighted that excessive consumption of sugar can trigger a release of inflammatory messengers called cytokines, including histamine, but more research is needed for a complete understanding (1). Coming to dairy products like butter and cream present in caramel sauce, it is essential to note that these are not high histamine foods in their fresh state (2). However, dairy products can act as histamine-liberators, meaning they potentially cause the body to release stored histamine into the bloodstream (3). Vanilla, on the other hand, could work contrarily. A diminished histamine release has been associated with vanillin, the primary component of the extract from the vanilla bean in some studies. However, these impacts are not yet thoroughly understood (4). In conclusion, while components of caramel sauce may have potential impacts on histamine levels, no concrete research has established a direct link between consumption of caramel sauce and histamine levels. REFERENCES: 1. "Sugar's effects on the body." - Harvard Health 2. Maintz, Laura, and Natalija Novak. "Histamine and histamine intolerance." The American Journal of Clinical Nutrition, May 2007. 3. "Chronic Urticaria and Autoimmunity: Associations Found in a Large Population Study." The Journal of Allergy and Clinical Immunology: In Practice, May–June 2012. 4. Shimizu, A., et al. "Inhibitory effects of vanillin on antigen-induced degranulation in RBL-2H3 rat basophilic leukemia cells." The Journal of Nutritional Biochemistry, 1995.