Raisins Histamine Information

Raisins, naturally sweet and dehydrated grapes, have a variety of components that may influence histamine levels directly or indirectly. However, specific research addressing the impact of raisins on histamine levels is currently lacking, leading to ambiguity firmly establishing raisins' role as a histamine-level influencer. Therefore, we can primarily look at their constituents for potential effects. Raisins are rich in antioxidants like flavonoids and phenolic acids, which have been suggested to possess anti-inflammatory properties (1). While not directly studied in the context of histamine, these antioxidant properties lend potential for reducing histamine-associated inflammation. Moreover, some studies highlight that certain phenolic compounds can inhibit the activity of diamine oxidase, an enzyme that breaks down ingested histamine, indicating that foods rich in these phenolic compounds might slightly increase histamine levels (2). However, raisins have dietary fiber, known for its beneficial role in gut health (3). The gut microbiota plays a significant role in regulating histamine levels; a healthy gut might help maintain balanced histamine levels (4). To summarize, while specific research on the impact of raisins on histamine levels is sparse, their rich profile of antioxidants and dietary fiber has the potential to interact with the histamine metabolism pathways. Further research is necessary to ascertain whether these properties make raisins a histamine-increrasing product, a histamine liberator, or potentially beneficial for people with histamine intolerance. References: 1. Carlsen MH, Halvorsen BL, Holte K, et al. (2010). 'The total antioxidant content of more than 3100 foods, beverages, spices, herbs and supplements used worldwide'. Nutrition Journal. 9, 3. 2. Maintz L, Novak N. (2007). 'Histamine and histamine intolerance'. The American Journal of Clinical Nutrition. 22;85(5):1185-1896. 3. Slavin J. (2013). 'Fiber and Prebiotics: Mechanisms and Health Benefits'. Nutrients. 5, 1417–1435. 4. Sanchez-Perez S, et. al. (2019). 'Gut Bacteria Metabolites as Integral Regulators in Autoimmune, Neurodegenerative and Behavioral Disorders'. Int J Mol Sci. 20, 21:5611.