Margarita Histamine Information

Eating Margherita pizza can potentially impact histamine levels in the body, primarily due to the presence of ingredients such as tomatoes, cheese, and yeast-based dough all of which are known to have a high histamine content. Tomatoes, used in the sauce base of Margherita pizzas, are known to be high in histamine, and can trigger its release in the body. Additionally, they inhibit the action of diamine oxidase, an enzyme that breaks down histamine in the body, potentially leading to increased histamine levels (Skypala, I, et al, 2019). The cheese on Margherita pizzas, typically mozzarella, might also impact histamine levels. Although mozzarella is a quickly-ripened cheese and therefore typically has lower histamine levels than some of its aged counterparts, it can still contribute to the overall histamine load (Maintz L and Novak N, 2007). Lastly, the pizza dough, which often contains yeast, can also be a source of histamine. Yeast, particularly in baked goods, is classified among foods with a high histamine content (Maintz L and Novak N, 2007). However, there aren't any direct studies focusing on the effect of Margherita pizza on histamine levels, and this analysis is based on the common ingredients found in such a dish. Individual reactions may differ significantly due to personal tolerance levels, preparation methods, and the freshness of the food. References: 1. Skypala, I, Venter, C, Meyer, R et al. (2019). The development of a standardised diet history tool to support the diagnosis of food allergy. Clin Transl Allergy 9, 5. https://doi.org/10.1186/s13601-019-0241-1 2. Maintz L, Novak N. (2007). Histamine and histamine intolerance. Am J Clin Nutr. 85(5):1185-96. https://doi.org/10.1093/ajcn/85.5.1185.