File Powder Histamine Information

File powder is an essence commonly used in Louisiana Creole cuisine, derived from the leaves of Sassafras albidum, a deciduous tree. It's primarily used in the preparation of gumbo, acting as both a flavoring agent and a thickener. As sassafras is the only recognized source of file powder, the possible impact of this on histamine levels is directly reliant on the properties of sassafras leaves. Extensive research around the association of sassafras and histamine levels is lacking, thus, it would seem "This product has not been researched well enough to publish any information, our team is working hard on this. Data will be available soon". Nonetheless, sassafras has been acknowledged for its varied health benefits including alleviation of inflammation. Inflammation often occurs as an immune response, which may include histamine releasing from immune cells. Though we can't surmise a direct association between sassafras and histamine levels, the anti-inflammatory properties of sassafras could mean it plays a part in moderating immune responses, which in turn could possibly involve histamine regulation. It is essential to note, the FDA has cautioned against ingestion of sassafras or its components like safrole due to potential carcinogenic effects. Furthermore, file powder's impact on histamine levels could be influenced by what it's combined with in meals. For instance, if coupled with foods high in histamine like red wine, cheese, or smoked meats, the overall dish could potentially elevate histamine levels. References: 1. "Sassafras: Uses, Side Effects, Interactions, Dosage, and Warning". WebMD. Retrieved from: https://www.webmd.com/vitamins/ai/ingredientmono-370/sassafras 2. Buhner, S. H. (1996). Sacred and Herbal Healing Beers: The Secrets of Ancient Fermentation. Siris Books. 3. "Cancer-Causing Substances: National Cancer Institute". National Cancer Institute. Retrieved from: https://www.cancer.gov/about-cancer/causes-prevention/risk/substances 4. Maintz, L., Novak, N. (2007). "Histamine and histamine intolerance". American Journal of Clinical Nutrition. 85(5): 1185-96.