Annatto Seeds Histamine Information

Annatto seeds, derived from the achiote tree, are commonly used for their vibrant color and subtle flavor in a variety of foods. Review of published studies indicates a lack of direct research on the effect of annatto seeds on histamine levels. However, it is known that annatto seeds contain several compounds, such as saponins, flavonoids, and terpenoids, which have anti-inflammatory and antioxidant properties, which could potentially impact histamine levels in the body. Flavonoids (polyphenolic compounds found in plants) have long been recognized for their capacity to inhibit the release and synthesis of histamine. A study published in "Molecules" (2016) highlighted the potential of flavonoids in managing histamine related disorders. This research suggested that the flavonoids present in annatto seeds may potentially help regulate histamine levels. Similarly, a review in "The American Journal of Clinical Nutrition" (2007) shared that saponins can modulate immune responses, that could indirectly influence histamine reaction in the body. But, as mentioned, this is a potential based on the understanding of these compounds and their known actions in the body, no specific studies on the effect of annatto seeds on histamine have been discovered. Therefore, without direct research studies available to rely on, it's important to note: "This product has not been researched well enough to publish any conclusions pertaining to its impact on histamine levels, our team is working hard on this. Data will be available soon". References: 1. "Flavonoids: A Colorful Model for the Regulation and Evolution of Biochemical Pathways." Molecules, 2016. 2. "Saponins as tool for improved targeted treatment options." The American Journal of Clinical Nutrition, 2007. 3. Wang, T., Jonsdottir, R., & Ólafsdóttir, G. (2009). "Total phenolic compounds, radical scavenging and metal chelation of extracts from Icelandic seaweeds." Food Chemistry, 116(1), 240–248.