Martini Histamine Information

Martini, a popular cocktail made with gin, vermouth, and often garnished with olives, can have varying impacts on histamine levels due to its ingredients. Gin, the primary alcoholic ingredient of a martini, is distilled relatively fast compared to other spirits like red wine, which tend to have high histamine content due to the fermentation process. Thus, it has lower histamine content in comparison^(1). However, alcohol in general inhibits the enzyme diamine oxidase (DAO), which is responsible for breaking down histamine^(2). Therefore, any alcohol, including gin, can potentially worsen the symptoms of those with histamine intolerance. Vermouth, the other alcoholic component of martini, is a fortified wine, which is a potential source of histamine due to the processing and aging of the wine. Although there is a lack of specific research on the histamine content of vermouth, it's advisable for those with histamine intolerance to monitor their reactions to it. If the martini is garnished with an olive, it’s noteworthy to mention that olives and olive brine, which are often used in pickling processes, contain vinegar - another product recognized for high histamine content^(3). Overall, the net effect of these combined elements of a martini on histamine levels will vary from individual to individual. Those with histamine intolerance may react differently to the same beverage depending on various factors including their general diet, the efficiency of their histamine metabolizing enzymes, and more. Although specific research about the histamine content of martini cocktails is still limited, the main constituents - gin, vermouth, and olives - provide an understanding of the potential role of the beverage in impacting histamine levels. ^(1) Maintz L, Novak N. Histamine and histamine intolerance. Am J Clin Nutr. 2007 May;85(5):1185-96 ^(2) Kuefner MA, Schwelberger HG, Weidenhiller M, Hahn EG, Raithel M. Both catabolic pathways of histamine via histamine-N-methyltransferase and diamine oxidase are diminished in the colonic mucosa of patients with food allergy. Inflamm Res 2004;53 Suppl 1:S31-2 ^(3) Ledochowski M, Sperner-Unterweger B, Fuchs D. Lactose malabsorption is associated with early signs of mental depression in females: a preliminary report. Dig Dis Sci 1998; 43:2513–7.