Espresso Histamine Information

Espresso, like other forms of coffee, is primarily composed of caffeine and water. While individual blends and roasts may include additional ingredients, these are the main constituents. Caffeine is a natural stimulant that can directly affect the histamine levels within the body. Research studies, such as that published in The American Journal of Clinical Nutrition (1), have shown that caffeine blocks the action of adenosine, a compound in the body that promotes the release of histamine. As such, consumption of caffeine can potentially contribute to a decrease in histamine levels, improving symptoms in individuals with histamine intolerance. However, the water used to make espresso and other coffee drinks can affect histamine content depending on its source. If tap water is used, there's a possibility of it containing chlorine, which is a known histamine liberator(2). In conclusion, espresso can have a mixed impact on histamine levels due to its caffeine content that can lower histamine levels, and its water content that may promote histamine release if it contains chlorine. Further research is needed to determine the exact effect, which may vary based on individual sensitivity and other dietary factors. (1) James J.S. “Caffeine and progression of AIDS” Clin Infect Dis. 1996;22(5):867–8. (2) Miyake Y, Yamasaki M, Yokooji T, Osuna H, Muroi N, Matsuo H. "Histamine Liberators in Water and Wines: An Immunological Risk for Histamine Intolerance." Int J Mol Sci. 2019;20(18):4561.