Lemon Balm Histamine Information

Lemon balm, scientifically known as Melissa officinalis, is a herb celebrated for its notable health benefits. While there is limited direct research and related reference regarding lemon balm's effect on histamine levels, its ingredients have exhibited certain properties that can potentially impact histamine. Firstly, it's essential to note that lemon balm contains rosmarinic acid and flavonoids known for their anti-inflammatory and antioxidant properties. Rosmarinic acid inhibits histamine release from mast cells triggered by antigens, hence potentially reducing histamine levels [1]. However, caution is needed, as everyone’s reaction to foods (including lemon balm) is uniquely individual, and lemon balm is not cited on major lists of low-histamine foods, nor on lists of histamine-liberating foods or those that inhibit DAO, the enzyme that helps degrade histamine in the body [2]. The impact can vary from person to person, and anyone with histamine intolerance and related concerns should consult a healthcare provider before making considerable changes in their diet or introducing new herbs. References: 1. Sanbongi C, Takano H, Osakabe N, Sasa N, Natsume M, Yanagisawa R, Inoue KI, Sadakane K, Ichinose T, Yoshikawa T. Rosmarinic acid in perilla extract inhibits allergic inflammation induced by mite allergen, in a mouse model. Clin Exp Allergy. 2004 Jun;34(6):971-7. doi: 10.1111/j.1365-2222.2004.1953.x. PMID: 15196278. 2. Maintz L, Novak N. Histamine and histamine intolerance. Am J Clin Nutr. 2007 May;85(5):1185-96. doi: 10.1093/ajcn/85.5.1185. PMID: 17490952.