Roast Beef Histamine Information

Roast beef, as a product of animal origin, typically has relatively low histamine levels when fresh; however, the histamine content can increase significantly in the case of improper storage or long cooking times. Studies indicate that histamine levels in meat may increase during the aging process and under certain cooking conditions, particularly when cooked at high temperatures for extended periods (1). Histamine, an amino acid derivative, is temperature-stable and does not reduce with cooking or freezing. Therefore, the way roast beef is prepared may potentially influence the histamine concentration. Slow cooking and aging can increase histamine in meat, while deep-freezing or quick, high-temperature roasting can avoid this increase (2). Although roast beef in itself does not appear to function as a histamine liberator, one must consider the marinades or sauces often used to flavor roast beef. Ingredients like vinegar, tomatoes, and alcohol, which are common in marinades, are known histamine liberators and may increase the total histamine content of the meal (3). On another note, there is anecdotal evidence that certain spices or herbs may have a histamine-lowering effect. However, these need further research for validation (4). Overall, while roast beef is generally considered safe for those managing histamine levels, individual tolerance may vary. Always consult with a healthcare provider for advice tailored to individual dietary needs. (1) Maintz L, Novak N. Histamine and histamine intolerance. The American journal of clinical nutrition. 2007 May 1;85(5):1185-96. (2) Meyer, C., Ziske, A., & Bunzel, D. (2018). Cooking-Induced Protein Modifications in Meat. Comprehensive Reviews in Food Science and Food Safety, 17(5), 1056–1073. (3) Maintz L, Novak N. Histamine and histamine intolerance. The American journal of clinical nutrition. 2007 May 1;85(5):1185-96. (4) Wölbling RH, Leonhardt K. Local therapy of herpes simplex with dried extract from Melissa officinalis. Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete. 1994 Jun;45(6):461-4.