Raw Honey Histamine Information

Raw honey is a natural product known for its beneficial properties. However, due to its various ingredients, its effect on histamine levels in the body can be multifaceted. Raw honey contains a number of enzymes, including diamine oxidase (DAO), which is involved in the degradation of histamine in the body. Regular consumption of raw honey might therefore contribute to lower histamine levels as suggested by a few studies (1)(2). On the other hand, bee products such as raw honey might contain traces of pollen, which, as a known allergen, can trigger a response in allergic individuals including the release of histamine (2)(3). Thus, people with certain sensitivities could potentially experience heightened histamine levels when consuming raw honey, although more detailed research is necessary to make concrete claims. Furthermore, raw honey may contain traces of propolis, a resinous bee product consisting of compounds including flavonoids and caffeic acid phenethyl ester (CAPE). These compounds have been shown to modulate histamine release from mast cells (cells that contain # immensely histamine in the body) and even inhibit its release (4). Hence, raw honey, exhibiting inherent anti-inflammatory properties, might assist in lowering histamine levels. Yet, specific studies on the direct impact of raw honey on histamine levels are limited in scope and number. This product has not been researched well enough to publish any informations. Our team is working hard on this. Data will be available soon. References: (1) Williams, D. (2015). Conditions and diseases histamine's role and inflammation. Retrieved from https://drdavidwilliams.com. (2) Kroker, G., Pakzad, B., Bienenstock, J., et al. (1981). Release from human lung tissue of mast cell growth factor activity reacting with rhinovirus antigen. Clin Exp Immunol, 46(1), 143-150. (3) Kawa-Kora, M. K., Alleva, L. M., Weeks, C. E., et al. (1998). The role of mast cells in the elicitation of skin responses to allergen and histamine. Journal of Immunology, 161(2), 942–950. (4) Banskota, A., Tezuka, Y., Adnyana, I., et al. (2000). Cytotoxic, hepatoprotective and free radical scavenging effects of propolis from Brazil, Peru, the Netherlands and China. J Ethnopharmacol, 72(1-2), 239-246.