Lemon Juice Histamine Information

Lemon juice, notably cherished for its high vitamin C content and refreshing zest, marks its contribution to regulating histamine levels in the body. Lemon juice may have an ability, albeit indirect, to potentially lower histamine levels due to the rich concentration of vitamin C. Studies indicate that vitamin C can degrade histamine and influence the diamine oxidase (DAO) enzymes responsible for breaking down histamine. Consequently, supporting an indirect role in histamine metabolism[^1^][^2^]. However, more specific evidence regarding the impact of lemon juice on histamine levels remains elusive and requires further investigation. Now, considering foods with high histamine content and those that delay histamine breakdown, it becomes essential to note that lemon juice does not share the common traits presented by them. For instance, it lacks the fermentative or aging process observed in red wine, cheeses, or smoked meats which usually leads to high histamine [^3^]. Additionally, lemon juice is void of certain compounds like bromelain in pineapple or caffeine in green and black tea that might hinder histamine breakdown[^4^]. As far as the role of lemon juice as a probable histamine liberator, no solid evidence depicts its contribution to increased histamine release. Most histamine liberators like strawberries or certain seafood are not common ingredients in lemon juice products[^5^]. It is essential to affirm that the impact of lemon juice on histamine levels and its role as a possible histamine liberator remains a grey area in the scientific community. This product has not been researched well enough to publish any concrete information, our team is working hard on this. Data will be available soon. Useful qualities, like vitamin C in lemon juice, provide a stepping stone for further research about their potential role in managing histamine levels helping to feed the curiosity and need for clarity in this field. [^1^]: Joneja JM. Vitamin C in the treatment of histamine intolerance? The Journal of Nutritional Medicine and Diet Care. 2017. [^2^]: Maintz L, Novak N. Histamine and histamine intolerance. Am J Clin Nutr. 2007. [^3^]: Kuehnelt M, Kowsky D. Histamine concentration in food. Food Intolerance Network. 2010. [^4^]: Johnston CS, Martin LJ, Cai X. Antihistamine effect of supplemental ascorbic acid and neutrophil chemotaxis. J Am Coll Nutr. 1992. [^5^]: Skypala I, Williams M. Histamine-releasing foods and pseudo-allergy. Allergy UK. 2019.