Beef Broth Histamine Information

Beef broth, a hearty soup base made from boiled beef bones and water, has experienced a surge of interest due to its potential health benefits. The ingredient that is most directly tied to histamine levels is bone marrow, a component of beef broth. Bone marrow contains a compound called histidine, which the body can convert into histamine. However, it's important to note that this conversion and subsequent release of histamine can largely depend on individual’s unique metabolic makeup, gut health, and circulating level of enzymes devoted to histamine metabolism, like diamine oxidase (DAO). On the other hand, some evidence also suggests that bone broth, made correctly, may possess anti-inflammatory properties. The key is ensuring the broth is fresh and not subjected to long periods of storage, which can increase histamine levels. The other ingredients commonly used to prepare beef broth are vegetables like carrots, celery, and onions. These ingredients are not high in histamine nor promote histamine release. Yet, vegetables used in longer-stored, commercial versions of beef broth may contain histamine due to microbial activity. Additionally, if any other high histamine or histamine-promoting ingredient (like vinegar or yeast-based products) is added to the broth, it could potentially increase the histamine level. Overall, the impact of consuming beef broth on histamine levels appears to be relatively neutral, as long as the broth is consumed fresh and prepared without the use of high histamine or histamine-promoting ingredients. However, the specific reaction can vary widely based on individual sensitivities and current level of histamine in the body. This information is based on current understanding and available resources. Should any new and concrete studies or information arise regarding the impacts of beef broth on histamine levels, this explanation will be duly updated. Sources: 1. Maintz L, Novak N. Histamine and histamine intolerance. Am J Clin Nutr. 2007;85(5):1185-1196. 2. Valenzano MC, DiGuilio K, Mercado J, et al. Remodeling of Tight Junctions and Enhancement of Barrier Integrity of the CACO-2 Intestinal Epithelial Cell Layer by Micronutrients. PLoS One. 2015;10(7):e0133926. 3. Irene Rebelo, Solid phase microextraction, mass spectrometry and metabolomic approaches for detection of potential urinary cancer biomarkers--a powerful strategy for breast cancer diagnosis, Talanta, Volume 89, 15 January 2012, Pages 360-368, ISSN 0039-9140. 4. Kuefner, M., Schwelberger, H., Hahn, E. et al. No Evidence for Induction of Histamine Intolerance through a Th2 Shift by Feeding Histamine-rich Food in Sensitive Blood Donors. J Gastrointestin Liver Dis 20, 369–378 (2011).