Fettuccine Alfredo Histamine Information

Fettuccine Alfredo, a popular Italian dish consists of mainly three key ingredients: fettuccine pasta, butter, and hard cheese (like Parmesan). Fettuccine pasta by itself contains negligible amounts of histamine, as histamine is typically found in aged, fermented, or spoiled foods, unlike freshly made or dried pasta (Pasta & Histamine. TMIH. Available online: https://mastcellfriendly.com/histamine-in-pasta/). Butter also has a negligible histamine content for the same reasons as pasta, as it is not an aged or fermented product either. In addition, there is no widely accepted scientific evidence to suggest it acts as a histamine liberator (Historamine Intolerance and DAO. The Happy Kitchen. Available online: https://rhkthehappykitchen.com/histamine-intolerance-and-dao/). However, the hard cheese, which is often an age-dependent ingredient, does contain higher histamine content. Aged cheeses, such as Parmesan often used in Fettuccine Alfredo, can contain a significant amount of histamine due to the bacterial fermentation process they undergo during aging. The longer a cheese is aged, the higher its histamine content tends to become (Histamine and histamine intolerance. American Journal of Clinical Nutrition. Available online: https://academic.oup.com/ajcn/article/85/5/1185/4633007). Therefore, overall, consuming Fettuccine Alfredo could raise histamine levels due to its cheese content. However, whether it raises it enough to trigger histamine symptoms will vary based on the individual's tolerance, as well as the quantity and type of cheese used. Among the ingredients of Fettuccine Alfredo, none are known to lower histamine levels, based on the current scientific literature. In summary, while the pasta and butter in Fettuccine Alfredo are unlikely to significantly impact histamine levels, the aged cheese commonly used in the dish can contribute to higher histamine levels in individuals who are sensitive to histamine.