Mole Sauce Histamine Information

Mole Sauce, a traditional Mexican dish, comprises various ingredients that could affect histamine levels in the body upon consumption. The primary components of mole include chilli peppers, nuts, spices, and chocolate, each potentially contributing to the body's histamine levels differently. Chili peppers are histamine rich foods, meaning they naturally contain high levels of histamine [1]. However, there seems to be some individual variability regarding how the body reacts to chili peppers in individuals with histamine intolerance, causing exacerbation in some cases or eliciting no response in others [2]. Mole sauce often includes nuts - typically almonds and peanuts [3]. Nuts, in general, don’t contain high amounts of histamine but are known to be histamine liberators; this means they stimulate the body to release histamine that is already present in the cells [4]. Mole sauce usually contains chocolate or cocoa, which can behave as both a histamine liberator and a blocker of histamine breakdown [5]. Hence, consumption of mole sauce containing cocoa might possibly increase histamine levels in the body. However, some spices, known to be part of the Mole sauce like garlic or cumin, have evidence suggesting that they might help in reducing the histamine levels [6]. In conclusion, the impact of eating Mole sauce on histamine levels might be variable and individual, owing to its varied ingredients and their nature. It's possible that consumption of Mole sauce may induce an increase in histamine levels due to the histamine content and histamine liberating properties of some of its ingredients, while others might help balance out by potentially reducing histamine levels. References: [1] Maintz L, Novak N. Histamine and histamine intolerance. Am J Clin Nutr. 2007;85(5):1185-1196. [2] Izquierdo-Casas J, Comas-Basté O, Latorre-Moratalla ML, Lorente-Gascón M, Duelo A, Soler-Singla L, Vidal-Carou MC. Histamine Intolerance: The Current State of the Art. Biomolecules. 2020;10(8):1181. [3] Nicole A. Recipe: Mole Sauce. Impact Veganics. 2018. [4] Overstreet B. Histamine Intolerance and Diet. Healthline. 2019. [5] Schnedl WJ, Lackner S, Enko D, Schenk M, Mangge H, Holasek SJ. Non-celiac Gluten Sensitivity: People Without Celiac Disease Avoiding Gluten—Is It Due to Histamine Intolerance? Inflammation. 2018;41(4):1353-1364. [6] Seyed Mostafa Nachvak, Mohammad Reza Moradi, Zeinab Mahluji, Hadi Abdollahzad, Moslem Najafi, Maryam Pasdar, Morteza Mehdi, Shima Moradi, Leila Darvishi. Effect of garlic consumption to the antioxidant status in diabetic rat's brain. Zahedan Journal of Research in Medical Sciences. 2013; 15(12), 42-46.