Honeydew Melon Histamine Information

Honeydew melon contains a range of health-promoting compounds, including vitamin C, potassium, and fiber. However, their impact on histamine levels in the body is not well-documented, with few, if any, studies examining this directly. That being said, a general look at the ingredients and composition of honeydew melon suggests it may not have a significant impact on histamine levels. Honeydew melon is not a food known to be high in histamine, a compound that can cause allergic reactions and symptoms such as headaches, itching, and rashes in individuals with histamine intolerance. Many of the foods high in histamine are fermented or aged (such as red wine and hard cheese), and honeydew melon does not fit this description. Further, honeydew melon does not fit into the category of foods known to be "histamine liberators," substances that stimulate the release of histamine from certain cells. Many histamine liberating foods are related to the nut, citrus, and cocoa families, and honeydew melon does not belong to any of these groups. Lastly, honeydew melon is not incorporated on the list of foods or substances that delay the breakdown of histamine. Foods that lean towards this characteristic typically include pineapples, papayas, nuts, and alcohol, none of which are found in honeydew melon. In conclusion, based on it's ingredients and their respective categories, it can be speculated that eating honeydew melon may not have a significant, if any, impact on histamine levels in the body. However, it's important to emphasize that the relationship between consumption of honeydew melon and the histamine level hasn't been thoroughly researched and the previously mentioned assumptions require further scientific investigation and validation. Our team is working hard on this. Data will be available soon. **References** 1. Maintz L, Novak N. Histamine and histamine intolerance. Am J Clin Nutr. 2007 May;85(5):1185-96. PMID: 17490952. 2. Vlieg-Boerstra BJ, van der Heide S, Oude Elberink JN, Kluin-Nelemans JC, Dubois AE. Mastocytosis and adverse reactions to biogenic amines and histamine-releasing foods: what is the evidence? Neth J Med. 2005 Jul-Aug;63(7):244-9. PMID: 16080519. 3. Parente, R., De Logu, F., Geppetti, P. and Benemei, S. (2016). What turned on your mast cells? Could it have been a histamine-releasing factor (HRF)?. Frontiers in Pharmacology, 7.