Penne Arrabbiata Histamine Information

Penne Arrabbiata is an Italian pasta dish comprising penne pasta tossed in a spicy tomato-based sauce. The essential ingredients are penne pasta, tomatoes, garlic, olive oil, and red pepper flakes. Tomatoes are known to be high in histamine. Thus, a major ingredient like tomatoes in Penne Arrabbiata means the dish could potentially increase histamine levels in the body [1]. However, a firm conclusion cannot be made as the histamine content can vary based on the type and ripeness of the tomato used [2]. Pasta, in general, has a low histamine content. However, if consumed with a high histamine tomato sauce as in Penne Arrabbiata, the overall histamine level of the meal can increase [3]. Garlic and olive oil do not significantly affect histamine levels and are safe to consume for individuals with histamine sensitivity [4]. Red pepper flakes can be histamine liberators, although their impact will likely depend on the individual's tolerance level and the quantity used [5]. Overall, although Penne Arrabbiata contains histamine-rich and histamine-releasing ingredients, it also includes ingredients that have low or no effect on histamine levels. Hence, individual reactions may vary, suggesting more research is needed. This evaluation is based on the general composition of Penne Arrabbiata. Some variations of the dish might include other ingredients like cheese or various type of meat, significantly affecting its histamine impact. References: [1] Maintz L, Novak N. Histamine and histamine intolerance. Am J Clin Nutr. 2007;85(5):1185-1196. [2] Histamine in Foods (food-info.net) [3] Histamine in Foods (food-info.net) [4] Joneja JV. The Health Professional's Guide to Food Allergies and Intolerances. American Dietetic Assoc.; 2013. [5] Jarisch R. Histamine intolerance in clinical practice. Dt Ärztebl Int. 2004;101(51-52):3477–3483.