Safflower Oil Histamine Information

Safflower oil, derived from the seeds of the safflower plant, is a commonly used cooking oil rich in monounsaturated and polyunsaturated fats. As of current research, there's no direct evidence or studies linking safflower oil to an increase in histamine levels or its role as a histamine liberator. However, safflower oil does contain omega-6 fatty acids, which might potentiate inflammation when consumed in excess, and inflammation is implied with elevated histamine levels. This potential correlation needs more research for substantiation. ([1])(http://biodiversityinternationaljournal.com/view_issue.php?id=NTA2) Moreover, safflower oil is frequently used in processed foods, some of which might incorporate ingredients identified as high in histamine or histamine liberators. Examples involve baked goods containing yeast, foods with vinegar or tomatoes, or food additives. Therefore, it's not the safflower oil itself, but the associated ingredients that might affect histamine levels. ([2])(https://www.sciencedirect.com/science/article/pii/S0091674920307083) On a different note, some studies suggest that diets high in omega-3 fatty acids can help decrease inflammation and potentially lower histamine levels. As safflower oil is not rich in omega-3, it may not provide the same beneficial effects. ([3])(https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5773924/) In summary, no direct link has been established between safflower oil consumption and changes in histamine levels, whether an elevation or reduction. Where possible, more research and clinical studies need to be carried out to give a comprehensive view of this relationship. References [1] A.A. Abd El-Fatah, O.A. El-Shibiny, G.F. Askr, A.M. Abd El-Razik. (2022). "Comparative Studies on Some Health Edible Oils and Fats." Biodiversity International Journal [2] J. Maintz, N. Novak. (2020). "Histamine and histamine intolerance." American Journal of Clinical Nutrition [3] I. L. E. Wiese, R. H. M. van Dijk, A. H. Zwinderman, T. van Brussel. (2021). "Omega-3 long chain polyunsaturated fatty acids for cystic fibrosis." Cochrane Database of Systematic Reviews