Zinfandel Histamine Information

Zinfandel, particularly red Zinfandel, is a variety of wine that can potentially impact histamine levels in the human body. Similar to other red wines, Zinfandel is believed to have higher histamine content [1]. The fermentation process and the red grape skins rich in polyphenols are factors contributing to this increase in histamine levels[1]. Beyond the histamine content, Zinfandel, like other alcoholic beverages, has the potential to interfere with histamine degradation. Alcohol inhibits the enzyme diamine oxidase (DAO), responsible for the breakdown of histamine in the body[2]. In this regard, consumption of Zinfandel can lead to a build-up of histamine which can further induce symptoms in individuals with histamine intolerance[3]. This includes headaches, itching, flushes, and other allergy-like symptoms[4]. However, it's essential to note that factors such as the type of grape, the aging process, and the fermentation method can influence the histamine content in wines like Zinfandel[3]. This said, there is currently insufficient scientific literature to provide more specific advice concerning the histamine content in Zinfandel. Therefore, more research is required for a comprehensive understanding of this subject. References: [1] Maintz L, Novak N. Histamine and histamine intolerance. The American Journal of Clinical Nutrition. 2007 May 1;85(5):1185-96. [2] Kacik J, Skwarło-Sońta K. Effects of alcohol on histamine metabolism in rat liver and brain. Agents and Actions. 1982 Dec;12(4):465-70. [3] Vally H, de Klerk N, Thompson PJ. Alcoholic drinks: important triggers for asthma. Journal of Allergy and Clinical Immunology. 2000 Mar 1;105(3):462-7. [4] Zimatkin SM, Anichtchik OV. Alcohol-histamine interactions. Alcohol and Alcoholism. 1999 Mar 1;34(2):141-7.