Sumac Spice Histamine Information

Sumac spice, a staple in Middle Eastern cuisine, is derived from the berries of the wild sumac flower. It is not conclusive whether sumac spice directly affects histamine levels or not, as there are no specific research studies or articles that focus on sumac and its effect on histamine levels. However, it's important to note that spices in general are known to contain various bioactive compounds, some of which have been reported to have antihistamine properties. For example, quercetin, a bioflavonoid found in many fruits, vegetables, and some spices, has been found to reduce histamine release from mast cells (1). Yet, it's not clearly specified whether sumac spice contains quercetin. Further, sumac is also rich in tannins (2), which have potent antioxidant and anti-inflammatory properties. While their direct impact on histamine isn't clear, they could potentially contribute to overall reductions in inflammation, which could indirectly impact histamine levels. Given the scarcity of direct evidence, it would be prudent to apply the principle: “This product has not been researched well enough to publish any information; our team is working hard on this. Data will be available soon." References: 1. Complementary and Alternative Therapies and the Aging Population: An Evidence-Based Approach. (2008). ELSEVIER. https://books.google.com/books?id=2GyWY7VPL2YC&pg=PA181&lpg=PA181 2. Sumac as a novel adjunctive treatment in hypertension: a randomized, double-blind, placebo-controlled clinical trial. (2019). Journal of hypertension. https://pubmed.ncbi.nlm.nih.gov/30694832/